Abstract:Catharsis,also know as the catharsis and descent,one of the eight diseases of TCM treatment.Drug use is flooded with ammonites,through a variety of approaches to achieve general guide shit in chuhe cleansed real hot,drink of attack by water.Acute cerebrovascular disease, stroke, is caused by the imbalance of yin and yang, the dysfunction of visceral organs, and the abnormal fluctuation of qi and blood, which ascends to the brain.Intervention on the gut-brain axis affects the synthesis and secretion of neurotransmitters, influencing the endocrine,nervous,and immune functions of the brain. This can lead to fluctuations in blood pressure and contribute to the development of cerebrovascular disease.This purgative is effective in relieving abdominal discomfort, expelling pathogenic factors, baancing the yin and yang energies, and acilitating the downward movement of qi and blood. By doing so, it subdues excessive energy and prevents it from disturbing the mind and spirit.And it is urgent to alleviate the retention of dampness and reduce the occurrence of other complications. By purging the bowels, blood coagulation is regulated, platelets are dispersed, bloodis diluted, cerebral blood flow is improved, neural function recoveryis promoted, and endotoxins are eliminated.Through the study of the gut-pancreas axis, gut hormones can regulate blood sugar levels by promoting the secretion of glucagon.Enzymes in the gut can exacerbate the progression of pancreatitis. The function of the gut barrier is influenced by the gut microbiome.An imbalanceof the microbial community leads to increasedmucosal permeability and the translocation ofmicroorganisms, which accelerates the progression of the disease.The relationship between the pancreas and theintestines plays a very important role in the occurrence and development of pancreatic diseases.Comprehensive treatment methods including internal, external, and acupuncture can effectively controlthe disease.The lungs and large intestine have a mutual influence on each other.The dryness and heat in the lungs can damage the fluid in the large intestine, leading to dry and hard stools.Activating the passageto promote bowel movements can help remove toxins and reduce the amount ofinflammatory mediators in the intestines.When inflammatory factors are overactivated, it can result in damage to the intestinal barrier function,increased permeability, and the entry of toxins through the lymphatic system into the pulmonary circulation and systemic circulation, acceleratingdamage to the organs. By using laxative methods to eliminate pathogenic microbial colonies,maintaining the function of the intestinal wall.and promoting recovery from the disease.It plays an important role in the treatment of severe patients with ICU.
Keywords : Purgation;Acute cerebrovascular disease;Severe pneumonia; Severe acute pancreatitis
参考文献 [1] 于永春.下法在中风病中的应用研究例析[J].中医药学刊,2003,21(12):2118.
[2] 邹明辉.通腹化痰活血复方对急性脑缺血大鼠的治疗作用[J].中国中西医结合杂志,1991,11(ZI):192.
[3] 徐建昭,马岩石,王丹萍,等.基于微生物-肠-脑”轴的肠道菌群参与抑郁症相关研究进展[J].食品科学,2023,44(05):383-391.
[4] 王永湘.中医下法治疗重症急性胰腺炎 40 例临床研究[J].中国医药指南,2012,10(26):249-250.
[5] Mederos MA, Reber HA, Girgis MD. Acute Pancreatitis: A Review [J]. JAMA, 2021, 325:382-390.
[6] 龚亮,宋晓,苏磊,等.急性胰腺炎肠道微生态的研究进展[J],中华临床营养杂志,2021.29:308-314.
[7] 李金强,惠亮亮.急性胰腺炎患者肠道菌群的研究进 展[J].中国 微生 态学 杂志 ,2024,36(12):1480-1484.
[8] A famsin-glucagon axis mediates glucose homeostasis 12-19, doi:10.1016/ [J]. cmet.2024. 11.008.
[9] You D, Wu Y, Lu M, Shao F, Tang Y, Liu S, Liu L, Zhou Z, Zhang R, Shen S, Lange T, Xu H, Ma H, Yin Y, Shen H, Chen F, Christiani DC, Jin G, Zhao Y. A genome-wide cross-trait analysis characterizes the shared genetic architecture between lung and gastrointestinal diseases. [J] Nat Commun. 2025 Ma 28: 16(1):3032.
[10] 李蓉蓉,赵冰,陈丹丹,李江楠,修明慧,宋忠阳,和建政,张志明,中医药通过“肠-肺轴”治疗急性肺损伤的研究进展[J].中草
药,2025,56(9):3305-3315.
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